Search on: NAV1.2 ALPHA SUBUNIT 
Descriptors Found: 1
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Descriptor English:   NAV1.2 Voltage-Gated Sodium Channel 
Descriptor Spanish:   Canal de Sodio Activado por Voltaje NAV1.2 
Descriptor Portuguese:   Canal de Sódio Disparado por Voltagem NAV1.2 
Synonyms English:   NAV1.2 alpha Subunit
SCN2A Sodium Channel alpha Subunit
Sodium Channel Protein Type 2 Subunit alpha
Sodium Channel, Voltage-Gated, Type II, alpha 1
Sodium Channel, Voltage-Gated, Type II, alpha 1 Subunit
Type 2 Voltage-Gated Sodium Channel
Voltage-Gated Sodium Channel Type 2
Voltage-Gated Sodium Channel Type 2 alpha Subunit
NAV1.2 Voltage Gated Sodium Channel
Type 2 Voltage Gated Sodium Channel
Voltage Gated Sodium Channel Type 2
Voltage Gated Sodium Channel Type 2 Subunit alpha
Voltage Gated Sodium Channel Type 2 alpha Subunit
Voltage-Gated Sodium Channel Type 2 Subunit alpha  
Tree Number:   D12.776.157.530.400.875.750.200
D12.776.543.550.450.875.750.200
D12.776.543.585.400.875.750.200
D12.776.631.960.200
Definition English:   A voltage-gated sodium channel subtype that mediates the sodium ion permeability of excitable membranes. Defects in the SCN2A gene which codes for the alpha subunit of this sodium channel are associated with benign familial infantile seizures type 3, and early infantile epileptic encephalopathy type 11. 
Entry Combination - descr/qualif English:   NAV1.2 Voltage-Gated Sodium Channel/agonists use Voltage-Gated Sodium Channel Agonists
NAV1.2 Voltage-Gated Sodium Channel/antagonists & inhibitors use Voltage-Gated Sodium Channel Blockers
 
History Note English:   2013 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54948 
Unique Identifier:   D062551 

Occurrence in VHL: 		 

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